ACBD3 Antibody (PACO56150)
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주문- SKU:
- PACO56150
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ACBD3 Antibody (PACO56150) |
Antibody SKU: | PACO56150 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:300-1:500, IF:1:50-1:200 |
Species Reactivity: | Human, Rat |
Immunogen: | Recombinant Human Golgi resident protein GCP60 protein (263-366AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Rat kidney tissue. All lanes: ACBD3 antibody at 7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 61 kDa. Observed band size: 61 kDa. | |
IHC image of PACO56150 diluted at 1:500 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated ABC system. | |
IHC image of PACO56150 diluted at 1:500 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). |
Synonyms: | Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed], ACBD3, GCP60 GOCAP1 GOLPH1 |
UniProt Protein Function: | ACBD3: Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q42.12 Cellular Component: Golgi membrane; Golgi apparatus; membrane; mitochondrion; integral to membrane Molecular Function:protein binding; acyl-CoA binding Biological Process: transport; steroid biosynthetic process |
NCBI Summary: | The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H3P7 |
NCBI GenInfo Identifier: | 55777312 |
NCBI Gene ID: | 64746 |
NCBI Accession: | AAH45533.1 |
UniProt Secondary Accession: | Q9H3P7,Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3, B2RB29 |
UniProt Related Accession: | Q9H3P7 |
Molecular Weight: | 60,593 Da |
NCBI Full Name: | Acyl-Coenzyme A binding domain containing 3 |
NCBI Synonym Full Names: | acyl-CoA binding domain containing 3 |
NCBI Official Symbol: | ACBD3 |
NCBI Official Synonym Symbols: | PAP7; GCP60; GOCAP1; GOLPH1 |
NCBI Protein Information: | Golgi resident protein GCP60; golgi phosphoprotein 1; PKA (RIalpha)-associated protein; PBR- and PKA-associated protein 7; golgi complex associated protein 1, 60kDa; acyl-Coenzyme A binding domain containing 3; peripheral benzodiazepine receptor-associated protein PAP7 |
UniProt Protein Name: | Golgi resident protein GCP60 |
UniProt Synonym Protein Names: | Acyl-CoA-binding domain-containing protein 3; Golgi complex-associated protein 1; GOCAP1; Golgi phosphoprotein 1; GOLPH1; PBR- and PKA-associated protein 7; Peripheral benzodiazepine receptor-associated protein PAP7 |
Protein Family: | Golgi resident protein |
UniProt Gene Name: | ACBD3 |
UniProt Entry Name: | GCP60_HUMAN |