ACAA2 Antibody (PACO15244)
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주문- SKU:
- PACO15244
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ACAA2 Antibody (PACO15244) |
Antibody SKU: | PACO15244 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human ACAA2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15244(ACAA2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: NIH/3T3 cells, A172 cells, human liver cancer tissue, Primary antibody: PACO15244(ACAA2 Antibody) at dilution 1/375, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO15244(ACAA2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | 3-Ketoacyl-CoA thiolase, mitochondrial also known as acetyl-Coenzyme A acyltransferase 2 is an enzyme that in humans is encoded by the ACAA2 gene. Acetyl-Coenzyme A acyltransferase 2 is an acetyl-CoA C-acyltransferase enzyme. The encoded protein catalyzes the last step of the mitochondrial fatty acid, beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. |
Synonyms: | acetyl-CoA acyltransferase 2 |
UniProt Protein Function: | ACAA2: Abolishes BNIP3-mediated apoptosis and mitochondrial damage. Belongs to the thiolase family. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.1.16; Lipid Metabolism - fatty acid; Lipid Metabolism - fatty acid elongation in mitochondria; Transferase Chromosomal Location of Human Ortholog: 18q21.1 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:acetyl-CoA C-acyltransferase activity; protein binding; RNA binding Biological Process: fatty acid beta-oxidation |
NCBI Summary: | The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008] |
UniProt Code: | P42765 |
NCBI GenInfo Identifier: | 167614485 |
NCBI Gene ID: | 10449 |
NCBI Accession: | NP_006102.2 |
UniProt Secondary Accession: | P42765,Q9BUT6, |
UniProt Related Accession: | P42765 |
Molecular Weight: | |
NCBI Full Name: | 3-ketoacyl-CoA thiolase, mitochondrial |
NCBI Synonym Full Names: | acetyl-CoA acyltransferase 2 |
NCBI Official Symbol: | ACAA2 |
NCBI Official Synonym Symbols: | DSAEC |
NCBI Protein Information: | 3-ketoacyl-CoA thiolase, mitochondrial |
UniProt Protein Name: | 3-ketoacyl-CoA thiolase, mitochondrial |
UniProt Synonym Protein Names: | Acetyl-CoA acyltransferase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1 |
Protein Family: | 3-ketoacyl-CoA thiolase |
UniProt Gene Name: | ACAA2 |