ABI3 Antibody (PACO41222)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO41222
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ABI3 Antibody (PACO41222) |
Antibody SKU: | PACO41222 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human ABI gene family member 3 protein (1-366AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: ABI3 antibody at 5µg/ml + Mouse heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 40, 39 kDa. Observed band size: 40 kDa. | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO41222 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO41222 at dilution of 1:100. |
Background: | May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility. |
Synonyms: | ABI gene family member 3 (New molecule including SH3) (Nesh), ABI3, NESH |
UniProt Protein Function: | ABI3: May inhibit tumor metastasis. In vitro, reduces cell motility. Belongs to the ABI family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 17q21.3Cellular Component: cytoplasm; intracellular; lamellipodium; membraneMolecular Function: protein bindingBiological Process: cell motility; peptidyl-tyrosine phosphorylation; regulation of cell migration |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q9P2A4 |
NCBI GenInfo Identifier: | 206597502 |
NCBI Gene ID: | 51225 |
NCBI Accession: | NP_001128658.1 |
UniProt Secondary Accession: | Q9P2A4,Q9H0P6, C9IZN8 |
UniProt Related Accession: | Q9P2A4 |
Molecular Weight: | 38,450 Da |
NCBI Full Name: | ABI gene family member 3 isoform 2 |
NCBI Synonym Full Names: | ABI family member 3 |
NCBI Official Symbol: | ABI3 |
NCBI Official Synonym Symbols: | NESH; SSH3BP3 |
NCBI Protein Information: | ABI gene family member 3 |
UniProt Protein Name: | ABI gene family member 3 |
UniProt Synonym Protein Names: | New molecule including SH3; Nesh |
Protein Family: | ABI gene family |
UniProt Gene Name: | ABI3 |
UniProt Entry Name: | ABI3_HUMAN |