ABHD4 Antibody (PACO22113)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO22113
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ABHD4 Antibody (PACO22113) |
Antibody SKU: | PACO22113 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human ABHD4. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry analysis of paraffin-embedded human brain tissue using ABHD4 antibody. |
Background: | Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine By similarity. |
Synonyms: | Abhydrolase domain-containing protein 4; EC 3.1.1.-; Lyso-N-acylphosphatidylethanolamine lipase; Alpha/beta-hydrolase 4; |
UniProt Protein Function: | ABHD4: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily. |
UniProt Protein Details: | Protein type:Hydrolase; EC 3.1.1.- Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: endoplasmic reticulum membrane; lipid particle Molecular Function:hydrolase activity Biological Process: lipid metabolic process; phospholipid metabolic process; sequestering of lipid |
UniProt Code: | Q8TB40 |
NCBI GenInfo Identifier: | 74762601 |
NCBI Gene ID: | 63874 |
NCBI Accession: | Q8TB40.1 |
UniProt Secondary Accession: | Q8TB40,Q9H9E0, B4DDH7, |
UniProt Related Accession: | Q8TB40 |
Molecular Weight: | 20,239 Da |
NCBI Full Name: | Protein ABHD4 |
NCBI Synonym Full Names: | abhydrolase domain containing 4 |
NCBI Official Symbol: | ABHD4 |
NCBI Official Synonym Symbols: | ABH4 |
NCBI Protein Information: | protein ABHD4 |
UniProt Protein Name: | Protein ABHD4 |
UniProt Synonym Protein Names: | Alpha/beta hydrolase domain-containing protein 4 |
Protein Family: | Protein |
UniProt Gene Name: | ABHD4 |
UniProt Entry Name: | ABHD4_HUMAN |