Anti-ZMYND11 Antibody (CAB6327)
- SKU:
- CAB6327
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-ZMYND11 Antibody |
| Antibody SKU: | CAB6327 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 278-567 of human ZMYND11 (NP_997644.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SW620, U-937, Jurkat, Mouse kidney, Mouse lung, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 278-567 of human ZMYND11 (NP_997644.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PNHE LVWA KMKG FGFW PAKV MQKE DNQV DVRF FGHH HQRA WIPS ENIQ DITV NIHR LHVK RSMG WKKA CDEL ELHQ RFLR EGRF WKSK NEDR GEEE AESS ISST SNEQ LKVT QEPR AKKG RRNQ SVEP KKEE PEPE TEAV SSSQ EIPT MPQP IEKV SVST QTKK LSAS SPRM LHRS TQTT NDGV CQSM CHDK YTKI FNDF KDRM KSDH KRET ERVV REAL EKLR SEME EEKR QAVN KAVA NMQG EMDR KCKQ VKEK CKEE FVEE IKKL ATQH KQLI SQTK KKQW VNTS LF |
| Gene ID: | 10771 |
| Uniprot: | Q15326 |
| Cellular Location: | Chromosome, Nucleus |
| Calculated MW: | 60kDa/64kDa/66kDa/70kDa |
| Observed MW: | 71kDa |
| Synonyms: | ZMYND11, BRAM1, BS69, MRD30 |
| Background: | The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| UniProt Protein Function: | ZMYND11: Corepressor of transcription (Probable). |
| UniProt Protein Details: | Protein type:Tumor suppressor; DNA-binding; Transcription regulation Chromosomal Location of Human Ortholog: 10p14 Cellular Component: nucleoplasm; chromosome; nucleus Molecular Function:protein binding; DNA binding; zinc ion binding; transcription corepressor activity; methylated histone residue binding Biological Process: cell proliferation; negative regulation of JNK cascade; viral reproduction; transcription, DNA-dependent; chromatin modification; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of transcription from RNA polymerase II promoter; cell cycle Disease: Mental Retardation, Autosomal Dominant 30 |
| NCBI Summary: | The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15326 |
| NCBI GenInfo Identifier: | 425906058 |
| NCBI Gene ID: | 10771 |
| NCBI Accession: | Q15326.2 |
| UniProt Secondary Accession: | Q15326,Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3 B2R6G8, B7Z293, F6UH50, |
| UniProt Related Accession: | Q15326 |
| Molecular Weight: | 562 |
| NCBI Full Name: | Zinc finger MYND domain-containing protein 11 |
| NCBI Synonym Full Names: | zinc finger, MYND-type containing 11 |
| NCBI Official Symbol: | ZMYND11 |
| NCBI Official Synonym Symbols: | BS69; BRAM1; MRD30 |
| NCBI Protein Information: | zinc finger MYND domain-containing protein 11; adenovirus 5 E1A-binding protein; bone morphogenetic protein receptor-associated molecule 1 |
| UniProt Protein Name: | Zinc finger MYND domain-containing protein 11 |
| UniProt Synonym Protein Names: | Adenovirus 5 E1A-binding protein; Bone morphogenetic protein receptor-associated molecule 1; Protein BS69 |
| Protein Family: | Zinc finger MYND domain-containing protein |
| UniProt Gene Name: | ZMYND11 |
| UniProt Entry Name: | ZMY11_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ZMYND11 antibody (CAB6327) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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