Anti-WBP2 Antibody (CAB16312)

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SKU:
CAB16312
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Frequently bought together:

Description

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Antibody Name:Anti-WBP2 Antibody
Antibody SKU:CAB16312
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 15-140 of human WBP2 (NP_036610.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, A-375, C6, Rat spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 15-140 of human WBP2 (NP_036610.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VNNT ESIL MSYD HVEL TFND MKNV PEAF KGTK KGTV YLTP YRVI FLSK GKDA MQSF MMPF YLMK DCEI KQPV FGAN YIKG TVKA EAGG GWEG SASY KLTF TAGG AIEF GQRM LQVA SQAS RGEV PS
Gene ID:23558
Uniprot:Q969T9
Cellular Location:
Calculated MW:28kDa
Observed MW:28kDa
Synonyms:WBP2, GRAMD6, WBP-2
Background:The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment.
UniProt Protein Function:WBP2: Binds to the WW domain of YAP1, WWP1 and WWP2. Interacts with NEDD4.
UniProt Protein Details:

Protein type:Nuclear receptor co-regulator; Cell development/differentiation

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: nuclear chromatin

Molecular Function:chromatin DNA binding; protein binding

Biological Process: establishment of protein localization; positive regulation of gene expression, epigenetic; positive regulation of transcription from RNA polymerase II promoter

NCBI Summary:The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q969T9
NCBI GenInfo Identifier:25091539
NCBI Gene ID:23558
NCBI Accession:Q969T9.1
UniProt Secondary Accession:Q969T9,O95638,
UniProt Related Accession:Q969T9
Molecular Weight:28,087 Da
NCBI Full Name:WW domain-binding protein 2
NCBI Synonym Full Names:WW domain binding protein 2
NCBI Official Symbol:WBP2  
NCBI Official Synonym Symbols:WBP-2; GRAMD6  
NCBI Protein Information:WW domain-binding protein 2
UniProt Protein Name:WW domain-binding protein 2
Protein Family:WW domain-binding protein
UniProt Gene Name:WBP2  
UniProt Entry Name:WBP2_HUMAN
Anti-WBP2 Antibody (CAB16312)Western blot analysis of extracts of various cell lines, using WBP2 antibody (CAB16312) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 120s.

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