Anti-UGGT1 Antibody (CAB4866)
- SKU:
- CAB4866
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- UGGT1
- HUGT1
- UGCGL1
- UGT1
Frequently bought together:
Description
| Product Name: | UGGT1 Rabbit pAb |
| Product Code: | CAB4866 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | UGGT1, HUGT1, UGCGL1, UGT1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1456-1555 of human UGGT1 (NP_064505.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, 293T, HepG2, HL-60, HT-1080, Mouse liver, Mouse kidney, Rat liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1456-1555 of human UGGT1 (NP_064505.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PNNM IHQV PIKS LPQE WLWC ETWC DDAS KKRA KTID LCNN PMTK EPKL EAAV RIVP EWQD YDQE IKQL QIRF QKEK ETGA LYKE KTKE PSRE GPQK REEL |
| Gene ID: | 56886 |
| Uniprot: | Q9NYU2 |
| Cellular Location: | Endoplasmic reticulum lumen, Endoplasmic reticulum-Golgi intermediate compartment |
| Calculated MW: | 174kDa/177kDa |
| Observed MW: | 177kDa |
| UniProt Protein Function: | UGCGL1: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. Belongs to the glycosyltransferase 8 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transferase; EC 2.4.1.- Chromosomal Location of Human Ortholog: 2q14.3 Cellular Component: endoplasmic reticulum lumen; endoplasmic reticulum; ER-Golgi intermediate compartment Molecular Function:unfolded protein binding; UDP-glucose:glycoprotein glucosyltransferase activity Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification |
| NCBI Summary: | UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009] |
| UniProt Code: | Q9NYU2 |
| NCBI GenInfo Identifier: | 224471872 |
| NCBI Gene ID: | 56886 |
| NCBI Accession: | Q9NYU2.3 |
| UniProt Secondary Accession: | Q9NYU2,Q53QP2, Q53SL3, Q8IW30, Q9H8I4, |
| UniProt Related Accession: | Q9NYU2 |
| Molecular Weight: | 1555 |
| NCBI Full Name: | UDP-glucose:glycoprotein glucosyltransferase 1 |
| NCBI Synonym Full Names: | UDP-glucose glycoprotein glucosyltransferase 1 |
| NCBI Official Symbol: | UGGT1 |
| NCBI Official Synonym Symbols: | UGT1; HUGT1; UGCGL1 |
| NCBI Protein Information: | UDP-glucose:glycoprotein glucosyltransferase 1; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1 |
| UniProt Protein Name: | UDP-glucose:glycoprotein glucosyltransferase 1 |
| UniProt Synonym Protein Names: | UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1 |
| Protein Family: | UDP-glucose:glycoprotein glucosyltransferase |
| UniProt Gene Name: | UGGT1 |
| UniProt Entry Name: | UGGG1_HUMAN |
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