Anti-TAS1R3 Antibody (CAB10157)
- SKU:
- CAB10157
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-TAS1R3 Antibody |
| Antibody SKU: | CAB10157 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-570 of human TAS1R3 (NP_689414.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:4000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, LO2, Mouse liver, Mouse heart, Mouse brain, Rat kidney, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-570 of human TAS1R3 (NP_689414.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VAQA LHNT LQCN ASGC PAQD PVKP WQLL ENMY NLTF HVGG LPLR FDSS GNVD MEYD LKLW VWQG SVPR LHDV GRFN GSLR TERL KIRW HTSD NQKP VSRC SRQC QEGQ VRRV KGFH SCCY DCVD CEAG SYRQ NPDD IACT FCGQ DEWS PERS TRCF RRRS RFLA WGEP AVL |
| Gene ID: | 83756 |
| Uniprot: | Q7RTX0 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 93kDa |
| Observed MW: | 95-105kDa |
| Synonyms: | TAS1R3, T1R3 |
| Background: | The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. |
| UniProt Protein Function: | TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 3; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 1p36.33 Cellular Component: integral to membrane; plasma membrane Molecular Function:sweet taste receptor activity; taste receptor activity Biological Process: detection of chemical stimulus involved in sensory perception of sweet taste; G-protein coupled receptor protein signaling pathway; sensory perception of sweet taste; sensory perception of umami taste |
| NCBI Summary: | The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015] |
| UniProt Code: | Q7RTX0 |
| NCBI GenInfo Identifier: | 62299063 |
| NCBI Gene ID: | 83756 |
| NCBI Accession: | Q7RTX0.2 |
| UniProt Secondary Accession: | Q7RTX0,Q5TA49, Q8NGW9, |
| UniProt Related Accession: | Q7RTX0 |
| Molecular Weight: | 93,386 Da |
| NCBI Full Name: | Taste receptor type 1 member 3 |
| NCBI Synonym Full Names: | taste 1 receptor member 3 |
| NCBI Official Symbol: | TAS1R3 |
| NCBI Official Synonym Symbols: | T1R3 |
| NCBI Protein Information: | taste receptor type 1 member 3 |
| UniProt Protein Name: | Taste receptor type 1 member 3 |
| UniProt Synonym Protein Names: | Sweet taste receptor T1R3 |
| Protein Family: | Taste receptor |
| UniProt Gene Name: | TAS1R3 |
| UniProt Entry Name: | TS1R3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TAS1R3 antibody (CAB10157) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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