Anti-ROM1 항체 (CAB6970)

Antibody Name:	Anti-ROM1 Antibody
Antibody SKU:	CAB6970
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 126-263 of human ROM1 (NP_000318.1).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	MCF7, 293T, Mouse eye

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 126-263 of human ROM1 (NP_000318.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	PGSL DEAL EEGL VTAL AHYK DTEV PGHC QAKR LVDE LQLR YHCC GRHG YKDW FGVQ WVSS RYLD PGDR DVAD RIQS NVEG LYLT DGVP FSCC NPHS PRPC LQNR LSDS YAHP LFDP RQPN QNLW AQGC HEVL LEHL QD
Gene ID:	6094
Uniprot:	Q03395
Cellular Location:	Membrane, Multi-pass membrane protein
Calculated MW:	37kDa
Observed MW:	74kDa

Synonyms:

ROM1, ROM, ROSP1, RP7, TSPAN23

Background:

This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.

UniProt Protein Function:	ROM1: May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis. Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2. Belongs to the PRPH2/ROM1 family.
UniProt Protein Details:	Protein type:Membrane protein, multi-pass; Membrane protein, integral; Cell surface Chromosomal Location of Human Ortholog: 11q13 Cellular Component: integral to plasma membrane Disease: Retinitis Pigmentosa; Retinitis Pigmentosa 7
NCBI Summary:	This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008]
UniProt Code:	Q03395
NCBI GenInfo Identifier:	4506575
NCBI Gene ID:	6094
NCBI Accession:	NP_000318.1
UniProt Secondary Accession:	Q03395,B2R978,
UniProt Related Accession:	Q03395
Molecular Weight:	37,205 Da
NCBI Full Name:	rod outer segment membrane protein 1
NCBI Synonym Full Names:	retinal outer segment membrane protein 1
NCBI Official Symbol:	ROM1
NCBI Official Synonym Symbols:	ROM; RP7; ROSP1; TSPAN23
NCBI Protein Information:	rod outer segment membrane protein 1
UniProt Protein Name:	Rod outer segment membrane protein 1
UniProt Synonym Protein Names:	Tetraspanin-23; Tspan-23
Protein Family:	Rhomboid-like protease
UniProt Gene Name:	ROM1
UniProt Entry Name:	ROM1_HUMAN

Western blot - ROM1 Polyclonal Antibody (CAB6970)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)