Anti-PTGFR 항체 (CAB15088)

Antibody Name:	Anti-PTGFR Antibody
Antibody SKU:	CAB15088
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PTGFR (NP_000950.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Mouse, Rat
Positive Samples:	mouse liver, mouse brain, rat brain

Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PTGFR (NP_000950.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	ILMK AYQR FRQK SKAS FLLL ASGL VITD FFGH LING AIAV FVYA SDKE WIRF DQSN VLCS IFGI CMVF SGLC PLLL GSVM AIER CIGV TKPI FHST KITS K
Gene ID:	5737
Uniprot:	P43088
Cellular Location:	Cell membrane, Multi-pass membrane protein
Calculated MW:	29kDa/30kDa/32kDa/33kDa/40kDa
Observed MW:	40kDa

Synonyms:

PTGFR, FP

Background:

The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.

UniProt Protein Function:	PTGFR: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p31.1 Cellular Component: cytoplasm; extracellular region; integral to plasma membrane; plasma membrane Molecular Function:prostaglandin F receptor activity Biological Process: parturition; positive regulation of cell proliferation
NCBI Summary:	The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	P43088
NCBI GenInfo Identifier:	1172442
NCBI Gene ID:	5737
NCBI Accession:	P43088.1
UniProt Secondary Accession:	P43088,Q2KHP3, Q6RYQ6, Q9P1X4, A8K9Y0,
UniProt Related Accession:	P43088
Molecular Weight:	30,766 Da
NCBI Full Name:	Prostaglandin F2-alpha receptor
NCBI Synonym Full Names:	prostaglandin F receptor
NCBI Official Symbol:	PTGFR
NCBI Official Synonym Symbols:	FP
NCBI Protein Information:	prostaglandin F2-alpha receptor
UniProt Protein Name:	Prostaglandin F2-alpha receptor
UniProt Synonym Protein Names:	Prostanoid FP receptor
Protein Family:	Prostaglandin F2-alpha receptor
UniProt Gene Name:	PTGFR
UniProt Entry Name:	PF2R_HUMAN

Western blot analysis of extracts of various cell lines, using PTGFR antibody (CAB15088) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

ELISA Kits

Human Prostaglandin F2-alpha receptor (PTGFR) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)