Anti-NSMF Antibody (CAB4603)
- SKU:
- CAB4603
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NSMF
- HH9
- NELF
Frequently bought together:
Description
| Product Name: | NSMF Rabbit pAb |
| Product Code: | CAB4603 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NSMF, HH9, NELF |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 226-505 of human NSMF (NP_001124443.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | LO2, HT-29, 293T, BT-474, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 226-505 of human NSMF (NP_001124443.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FQTA TTTM QANF RKHL RMVG SRRV KAQT FAER RERS FSRS WSDP TPMK ADTS HDSR DSSD LQSS HCTL DEAF EDLD WDTE KGLE AVAC DTEG FVPP KVML ISSK VPKA EYIP TIIR RDDP SIIP ILYD HEHA TFED ILEE IERK LNVY HKGA KIWK MLIF CQGG PGHL YLLK NKVA TFAK VEKE EDMI HFWK RLSR LMSK VNPE PNVI HIMG CYIL GNPN GEKL FQNL RTLM TPYR VTFE SPLE LSAQ GKQM IETY FDFR LYRL WKSR QHSK LLDF DDVL |
| Gene ID: | 26012 |
| Uniprot: | Q6X4W1 |
| Cellular Location: | Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane, Nucleus, Nucleus envelope, Nucleus matrix, Nucleus membrane, Peripheral membrane protein, cell cortex, cytoskeleton, dendrite, postsynaptic cell membrane, postsynaptic density, synapse, synaptosome |
| Calculated MW: | 44kDa/56kDa/57kDa/59kDa/60kDa |
| Observed MW: | 70kDa |
| UniProt Protein Function: | NSMF: Couples NMDA receptor signaling to the nucleus. Influences outgrowth of olfactory axons and migration of LHRH neurons. Defects in NELF may be associated with idiopathic hypogonadotropic hypogonadism (IHH). IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: cortical cytoskeleton; nuclear membrane; neuron projection; nuclear matrix; postsynaptic density; dendrite; nuclear envelope; perikaryon; nucleoplasm; postsynaptic membrane; membrane; cytoplasm; synapse; nucleus; cell junction Molecular Function:calcium-dependent protein binding Biological Process: regulation of dendrite morphogenesis; regulation of neuron apoptosis; positive regulation of protein amino acid dephosphorylation; regulation of neuronal synaptic plasticity Disease: Hypogonadotropic Hypogonadism 9 With Or Without Anosmia |
| NCBI Summary: | The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] |
| UniProt Code: | Q6X4W1 |
| NCBI GenInfo Identifier: | 71152011 |
| NCBI Gene ID: | 26012 |
| NCBI Accession: | Q6X4W1.1 |
| UniProt Secondary Accession: | Q6X4W1,Q2TB96, Q6X4V7, Q6X4V8, Q6X4V9, Q8N2M2, Q96SY1 Q9NPM4, Q9NPP3, Q9NPS3, |
| UniProt Related Accession: | Q6X4W1 |
| Molecular Weight: | 530 |
| NCBI Full Name: | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NCBI Synonym Full Names: | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NCBI Official Symbol: | NSMF |
| NCBI Official Synonym Symbols: | HH9; NELF |
| NCBI Protein Information: | NMDA receptor synaptonuclear signaling and neuronal migration factor; nasal embryonic LHRH factor; nasal embryonic luteinizing hormone-releasing hormone factor |
| UniProt Protein Name: | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| UniProt Synonym Protein Names: | Nasal embryonic luteinizing hormone-releasing hormone factor; Nasal embryonic LHRH factor |
| Protein Family: | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| UniProt Gene Name: | NSMF |
| UniProt Entry Name: | NSMF_HUMAN |
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