| Background: | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. |
| UniProt Protein Function: | NLRP5: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. Belongs to the NLRP family. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 19q13.43 Cellular Component: mitochondrion; nucleolus |
| NCBI Summary: | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P59047 |
| NCBI GenInfo Identifier: | 215274029 |
| NCBI Gene ID: | 126206 |
| NCBI Accession: | P59047.2 |
| UniProt Secondary Accession: | P59047,Q86W29, A8MTY4, |
| UniProt Related Accession: | P59047 |
| Molecular Weight: | 134kDa |
| NCBI Full Name: | NACHT, LRR and PYD domains-containing protein 5 |
| NCBI Synonym Full Names: | NLR family pyrin domain containing 5 |
| NCBI Official Symbol: | NLRP5 |
| NCBI Official Synonym Symbols: | MATER; NALP5; PAN11; PYPAF8; CLR19.8 |
| NCBI Protein Information: | NACHT, LRR and PYD domains-containing protein 5 |
| UniProt Protein Name: | NACHT, LRR and PYD domains-containing protein 5 |
| UniProt Synonym Protein Names: | Mater protein homolog |
| Protein Family: | NACHT, LRR and PYD domains-containing protein |
| UniProt Gene Name: | NLRP5 |
