Anti-MYCL Antibody (CAB16301)
- SKU:
- CAB16301
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-MYCL Antibody |
| Antibody SKU: | CAB16301 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-180 of human MYCL (NP_005367.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, Mouse brain, Mouse lung, Rat brain, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-180 of human MYCL (NP_005367.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FYDY DCGE DFYR STAP SEDI WKKF ELVP SPPT SPPW GLGP GAGD PAPG IGPP EPWP GGCT GDEA ESRG HSKG WGRN YASI IRRD CMWS GFSA RERL ERAV SDRL APGA PRGN PPKA SAAP DCTP SLEA GNPA PAAP CPLG E |
| Gene ID: | 4610 |
| Uniprot: | P12524 |
| Cellular Location: | Nucleus |
| Calculated MW: | 24kDa/40kDa/43kDa |
| Observed MW: | 50kDa |
| Synonyms: | L-Myc, LMYC, MYCL1, bHLHe38, MYCL |
| Background: |
| UniProt Protein Function: | L-Myc: a proto-oncogenic transcription factor. Targets include CCL6 chemokine gene. Plays a role in cell proliferation, apoptosis and in the development of human tumors. |
| UniProt Protein Details: | Protein type:DNA-binding; Oncoprotein; Transcription factor Chromosomal Location of Human Ortholog: 1p34.2 Cellular Component: nucleus Molecular Function:DNA binding |
| UniProt Code: | P12524 |
| NCBI GenInfo Identifier: | 311033401 |
| NCBI Gene ID: | 4610 |
| NCBI Accession: | P12524.2 |
| UniProt Secondary Accession: | P12524,Q14897, Q5QPL0, Q5QPL1, Q9NUE9, A2A2C9, B4DJH2 |
| UniProt Related Accession: | P12524 |
| Molecular Weight: | 43,243 Da |
| NCBI Full Name: | Protein L-Myc |
| NCBI Synonym Full Names: | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NCBI Official Symbol: | MYCL |
| NCBI Official Synonym Symbols: | LMYC; L-Myc; MYCL1; bHLHe38 |
| NCBI Protein Information: | protein L-Myc |
| UniProt Protein Name: | Protein L-Myc |
| UniProt Synonym Protein Names: | Class E basic helix-loop-helix protein 38; bHLHe38; Protein L-Myc-1; V-myc myelocytomatosis viral oncogene homolog |
| Protein Family: | Protein |
| UniProt Gene Name: | MYCL |
| UniProt Entry Name: | MYCL_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MYCL antibody (CAB16301) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
 | Western blot analysis of extracts of A-549 cells, using MYCL antibody (CAB16301) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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