Anti-MRPL1 Antibody (CAB4947)

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SKU:
CAB4947
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MRPL1
BM022
L1MT
MRP-L1
Frequently bought together:

Description

Product Name:MRPL1 Rabbit pAb
Product Code:CAB4947
Size:20uL, 50uL, 100uL
Synonyms:MRPL1, BM022, L1MT, MRP-L1
Applications:WB, IHC
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 51-325 of human MRPL1 (NP_064621.3).
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:20 - 1:200
Reactivity:Human, Rat
Positive Samples:A-431, MCF7, HeLa, Jurkat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 51-325 of human MRPL1 (NP_064621.3).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KKTK KGAK EKTP DEKK DEIE KIKA YPYM EGEP EDDV YLKR LYPR QIYE VEKA VHLL KKFQ ILDF TSPK QSVY LDLT LDMA LGKK KNVE PFTS VLSL PYPF ASEI NKVA VFTE NASE VKIA EENG AAFA GGTS LIQK IWDD EIVA DFYV AVPE IMPE LNRL RKKL NKKY PKLS RNSI GRDI PKML ELFK NGHE IKVD EERE NFLQ TKIA TLDM SSDQ IAAN LQAV INEV CRHR PLNL GPFV VRAF LRSS TSEG LLLK IDPL LPKE VKNE ESEK EDA
Gene ID:65008
Uniprot:Q9BYD6
Cellular Location:Mitochondrion
Calculated MW:36kDa
Observed MW:37kDa
UniProt Protein Function:MRPL1: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:RNA-binding; Mitochondrial

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: nucleoplasm; mitochondrion; mitochondrial inner membrane; large ribosomal subunit

Molecular Function:structural constituent of ribosome

Biological Process: mitochondrial translation; organelle organization and biogenesis

NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
UniProt Code:Q9BYD6
NCBI GenInfo Identifier:239938694
NCBI Gene ID:65008
NCBI Accession:Q9BYD6.2
UniProt Secondary Accession:Q9BYD6,Q4W5B8, Q6IAG4, Q96BW3, Q9H793, Q9NRL5, A6NG03
UniProt Related Accession:Q9BYD6
Molecular Weight:325
NCBI Full Name:39S ribosomal protein L1, mitochondrial
NCBI Synonym Full Names:mitochondrial ribosomal protein L1
NCBI Official Symbol:MRPL1  
NCBI Official Synonym Symbols:L1MT; BM022; MRP-L1  
NCBI Protein Information:39S ribosomal protein L1, mitochondrial
UniProt Protein Name:39S ribosomal protein L1, mitochondrial
Protein Family:39S ribosomal protein
UniProt Gene Name:MRPL1  
UniProt Entry Name:RM01_HUMAN

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