Snaclec rhodocytin subunit alpha Antibody (PACO53938)
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주문- SKU:
- PACO53938
- Product type:
- Antibody
- Reactivity:
- Calloselasma rhodostoma
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | Snaclec rhodocytin subunit α Antibody (PACO53938) |
Antibody SKU: | PACO53938 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Calloselasma rhodostoma |
Immunogen: | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit α protein (1-136AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in Recombinant protein. All lanes: Rhodocytin subunit alpha antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 31 kDa. Observed band size: 31 kDa. |
Background: | Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbα (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. |
Synonyms: | Snaclec rhodocytin subunit α (Aggretin α chain) (Rhodoaggretin subunit alpha) |
UniProt Protein Function: | Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9I841 |
NCBI GenInfo Identifier: | 82174508 |
NCBI Gene ID: | |
NCBI Accession: | Q9I841.1 |
UniProt Secondary Accession: | Q9I841 |
UniProt Related Accession: | Q9I841 |
Molecular Weight: | 15,796 Da |
NCBI Full Name: | Snaclec rhodocytin subunit alpha |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | |
UniProt Protein Name: | Snaclec rhodocytin subunit alpha |
UniProt Synonym Protein Names: | Aggretin alpha chain; Rhodoaggretin subunit alpha |
Protein Family: | Snaclec rhodocytin |
UniProt Gene Name: | |
UniProt Entry Name: |