Human ALK/ACVRL1 Recombinant Protein (RPES4895)

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SKU:
RPES4895
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human ALK/ACVRL1 Recombinant Protein

Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair.

Product Name:Human ALK/ACVRL1 Recombinant Protein (RPES4895)
Product Code:RPES4895
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Serine/Threonine-Protein Kinase Receptor R3, SKR3, Activin Receptor-Like Kinase 1, ALK-1, TGF-B Superfamily Receptor Type I, TSR-I, ACVRL1, ACVRLK1, ALK1,HHT,HHT2,ORW2,SKR3
Accession:P37023
Sequence:Asp22-Gln118
Fusion tag:C-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human ALK-1 is produced by our Mammalian expression system and the target gene encoding Asp22-Gln118 is expressed with a Fc tag at the C-terminus.
Purity:> 90% as determined by reducing SDS-PAGE.
Mol Mass:37.6 kDa
AP Mol Mass:50-60 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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